CONCLUSIONS: Compared with 3% acyclovir cream, 1% penciclovir cream for the treatment of herpes simplex facialis can decrease the time of lesion healing and shorten the course of disease. It is an effective and safe topical agent. 结论:与3%阿昔洛韦软膏相比,1%喷昔洛韦软膏治疗颜面单纯疱疹能够使皮损较快消退,缩短病程,是一种安全有较的外用药物。